An-Najah News -  For the first time, in 2003, history was made after human genome was sequenced.technological improvements have enabled tweaks, adjustments, and additions, making the human genome the most accurate and complete Nevertheless, some gaps remain.

 Now, a new accomplishment  have been made for the first time, geneticists have closed some of those gaps, giving us the first complete, gap-free, end-to-end (or telomere-to-telomere) sequence of a human X chromosome.

A new technique called nanopore sequencing enables ultra-long-reads of DNA strands, providing a more complete and sequential assembly.

this technology reduces reliance on polymerase chain reaction, a technique that amplifies DNA by creating millions of copies of it.

The researchers were able to resolve this notoriously tricky structure by looking for slight variations in the repeats. 

These variations allowed the scientists to align and connect the long reads to form a complete sequence for the centromere.

sciencealert